Publications by authors named "N Joram"
Article Synopsis
- This study aimed to explore the link between the minimum lymphocyte count (Ly_Min) after cardiac surgery with cardiopulmonary bypass and the risk of infections within the first 30 days post-surgery.
- Researchers analyzed data from 1,428 pediatric cardiac surgeries and found that 8% of patients developed infections, with a significant correlation between lower Ly_Min and increased infection risk.
- The findings suggest that a Ly_Min below 1.105 x 10^9/L in the first postoperative day is a strong predictor of infections, highlighting the importance of monitoring lymphocyte levels in pediatric patients after surgery.
Article Synopsis
- Sickle cell disease (SCD) affects many people worldwide, and a serious issue related to it is called acute chest syndrome (ACS), which can make patients really sick and require hospitalization.
- Researchers studied data from 1998 to 2022 about young people with SCD who needed a special treatment called ECMO to help their lungs.
- They found that 55.8% of patients survived ECMO treatment, but there were complications, and not all patients, especially young kids and some adults, survived when ECMO was used for heart resuscitation.
Objectives: Extracorporeal life support can lead to rapid reversal of hypoxemia but the benefits and harms of different oxygenation targets in severely ill patients are unclear. Our primary objective was to investigate the association between the Pa o2 after extracorporeal membrane oxygenation (ECMO) initiation and mortality in neonates treated for respiratory failure.
Design: Retrospective analysis of the Extracorporeal Life Support Organization (ELSO) Registry data, 2015-2020.
Article Synopsis
- Toxic shock syndrome (TSS) is a serious but rare illness that can lead to significant health problems, especially in children, and the study aimed to test the effectiveness and safety of intravenous immunoglobulin (IG) therapy compared to a control treatment in pediatric patients.
- The study involved a randomized clinical trial with 28 participants aged 1 month to 18 years, assessing the feasibility of the trial based on inclusion rates, protocol compliance, and data completeness over a follow-up period of one year.
- The results indicated that while the trial was feasible with a high inclusion rate and low missing data, there was no significant difference in clinical outcomes between the IG and control groups, although more adverse events were noted in the control group.
To evaluate the feasibility of continuous determination of the optimal mean arterial blood pressure (opt-MAP) according to cerebral autoregulation and to describe the opt-MAP, the autoregulation limits, and the time spent outside these limits in children within 48 h of cardiac surgery. Cerebral autoregulation was assessed using the correlation coefficient (COx) between cerebral oxygenation and MAP in children following cardiac surgery. Plots depicting the COx according to the MAP were used to determine the opt-MAP using weighted multiple time windows.
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