Publications by authors named "N Joffe"

Algal blooms drive global biogeochemical cycles of key nutrients and serve as hotspots for biological interactions in the ocean. The massive blooms of the cosmopolitan coccolithophore Emiliania huxleyi are often infected by the lytic E. huxleyi virus, which is a major mortality agent triggering bloom demise.

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Article Synopsis
  • * Mutations in specific residues of RPS3 (R116, R146, and K148) revealed differing impacts on translation initiation, start-codon accuracy, and gene translation patterns, especially for mRNAs with long 5'UTRs.
  • * RPS3's interaction with mRNA is crucial for SARS-CoV-2's ability to inhibit host translation and its mRNA stability, highlighting its role in viral manipulation of host cellular mechanisms.
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Medication adherence is challenging after pediatric hematopoietic stem cell transplant (HCT), particularly after hospital discharge. Post-HCT medication adherence is important to manage morbidity and mortality risk. Designing interventions that are effective and acceptable to caregivers is key to improving post-HCT medication adherence.

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Objective: Taking medications as prescribed after hematopoietic stem cell transplant (HCT) is key for ensuring children's survival; however, suboptimal medication adherence is common. Development of evidence-based interventions to improve medication adherence post-HCT is contingent upon understanding what adherence facilitators (i.e.

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Schistosomiasis is a disease caused by trematode parasites of the genus that affects approximately 200 million people worldwide. Schistosomiasis has been a persistent problem in endemic areas as there is no vaccine available, currently used anti-helmintic medications do not prevent reinfection, and most concerning, drug resistance has been documented in laboratory and field isolates. Thus, alternative approaches to curtail this human disease are warranted.

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