Publications by authors named "N Jnanendrappa"
Maintenance of oral health is a major challenge in dentistry. Different materials have been used to treat various dental diseases, although treatment success is limited by features of the biomaterials used. To overcome these limitations, materials incorporated with nanoparticles (NPs) can be used in dental applications including endodontics, periodontics, tissue engineering, oral surgery, and imaging.
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- The research focused on creating and characterizing in situ gels made from thermosensitive and mucoadhesive polymers for the sustained release of moxifloxacin, targeting periodontal diseases.
- The gels are in liquid form at room temperature but convert to gel upon reaching body temperature (37 °C), helping them adhere to the gum tissue for an extended period.
- Formulations P6 and C6 effectively released the drug over 8 hours and exhibited strong antimicrobial effects against key bacteria related to periodontal issues, suggesting they could improve patient adherence to treatment.