Antibacterial -trachyloban-19-oic acid and other constituents from G.W. Hu, Ngumbau & Q.F. Wang.

Phytochemical analysis of the twigs and leaves of , endemic to Kenya, yielded known compounds 3-(3',4'-dimethoxyphenyl)-prop-1-ene (, 3-(3',4'-dimethoxyphenyl)-propenal (), lupeol () and -trachyloban-19-oic acid (), and a tentatively new -clerodane diterpenoid, crotokinondoenolide (). -Trachy-loban-19-oic acid () showed good activity against a panel of drug-resistant strains of and spp with MIC -values of 25 g/mL.

Critical Insights on Preparation of Platelet-Rich Plasma in Tubes With a Thixotropic Gel Separator.

Thixotropic gels are the preferred choice in the collection of platelet-rich plasma as an easy solution to operator variability. One often unnoticed shortcoming is the entrapment of platelets in the gel layer's uppermost surface. We provide instructions to optimize platelet yield, ie, agitation to re-suspend platelets, setting the optimal G-force and time of centrifugation, and the essential use of a horizontal swing bucket centrifuge.

Insecticidal activity of essential oils from Piper aduncum against Ctenocephalides felis felis: a promising approach for flea control.

Piper aduncum L., a Brazilian medicinal plant, is known for its bioactive properties, including repellent and insecticidal effects. This study investigated the insecticidal potential of essential oils (EOs) from P.

Mining the chemical diversity of the hemp seed ( L.) metabolome: discovery of a new molecular family widely distributed across hemp.

Hemp ( L.) is a widely researched industrial crop with a variety of applications in the pharmaceutical, nutraceutical, food, cosmetic, textile, and materials industries. Although many of these applications are related to its chemical composition, the chemical diversity of the hemp metabolome has not been explored in detail and new metabolites with unknown properties are likely to be discovered.

Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia.

Pattern-type hair loss is a highly prevalent condition affecting the majority of men and women at some point in their lifetime. Although genetics and androgens are instrumental in the pathogenesis of this type of hair loss, it is increasingly recognized that inflammation, stress, and environmental factors play a central role. The few and widely used monotherapies approved by the US Food and Drug Administration, such as minoxidil or finasteride, are not efficacious in all people and cause adverse events that prevent patient compliance.