Publications by authors named "N J M van der Meer"
Article Synopsis
- The study explores the experiences and needs of informal caregivers (ICs) involved in shared decision-making (SDM) for patients over 70 with severe aortic stenosis (AS).
- It found that while most ICs prefer to be collaborative partners in decision-making, they often feel overlooked by healthcare professionals when it comes to discussing the patient's daily life.
- Higher perceived involvement in SDM is linked to better quality of life and lower distress for ICs, emphasizing the need for professionals to actively include them in the decision-making process.
Most teleost fish propel themselves with lateral body waves powered by their axial muscles. These muscles also power suction feeding through rapid expansion of the mouth cavity. They consist of muscle segments (myomeres), separated by connective tissue sheets (myosepts).
View Article and Find Full Text PDFMass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases. Unfortunately, high-dimensional analyses of CyTOF data remain quite demanding. Here, we deploy a bioinformatics framework that tackles two fundamental problems in CyTOF analyses namely (1) automated annotation of cell populations guided by a reference dataset and (2) systematic utilization of single-cell data for effective patient stratification.
View Article and Find Full Text PDFPathomechanisms of dementias involve increasing damage to neuronal energy metabolism, resulting in degeneration-related insulin resistance and glucose hypometabolism. In this case, ketone bodies can provide an alternative energy source. Supplementation with medium-chain triglycerides (MCTs), which can induce ketogenesis, may alleviate brain energy deficits and improve neuronal function.
View Article and Find Full Text PDFObjectives: To investigate the incidence of preoperative abnormal iron status and its association with packed red blood cell (PRBC) transfusion, postoperative major complications, and new onset of clinically significant disability in patients undergoing elective cardiac surgery.
Design: A prospective, observational multicenter cohort study.
Setting: Three cardiac surgical centers in the Netherlands between 2019 and 2021.