Publications by authors named "N J M Rijkhoff"

Purpose: To investigate the effect of dorsal clitoral nerve stimulation (DCNS) on bothersome urgency to defecate with or without fecal incontinence and the patient-reported discomfort or adverse effect with the method.

Methods: For dorsal clitoral nerve stimulation, a battery powered, handheld stimulator was used, set to a pulse width of 200 µs and a frequency of 20 Hz. One electrode was placed at the preputium of the clitoris and acted as cathode while an anode electrode was placed on the belly.

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Robust devices for chronic neural stimulation demand electrode materials which exhibit high charge injection ( ) capacity and long-term stability. Boron-doped diamond (BDD) electrodes have shown promise for neural stimulation applications, but their practical applications remain limited due to the poor charge transfer capability of diamond. In this work, we present an attractive approach to produce BDD electrodes with exceptionally high surface area using porous titanium nitride (TiN) as interlayer template.

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In this simulation study, a wireless passive LC-tank sensor system was characterized. Given the application of continuous bladder monitoring, a specific system was proposed in terms of coil geometries and electronic circuitry. Coupling coefficients were spatially mapped by simulation, as a function of both coil distance, and longitudinal and transverse translation of the sensor relative to the antenna.

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Objective: The goal of this study was to assess the electrochemical properties of boron-doped diamond (BDD) electrodes in relation to conventional titanium nitride (TiN) electrodes through in vitro and in vivo measurements.

Approach: Electrochemical impedance spectroscopy, cyclic voltammetry and voltage transient (VT) measurements were performed in vitro after immersion in a 5% albumin solution and in vivo after subcutaneous implantation in rats for 6 weeks.

Main Results: In contrast to the TiN electrodes, the capacitance of the BDD electrodes was not significantly reduced in albumin solution.

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Article Synopsis
  • The study examined how fibrous encapsulation impacts the electrochemical properties of porous titanium nitride electrodes in a living organism (in vivo).
  • Electrochemical impedance spectroscopy (EIS) was used to monitor inflammation and healing, revealing that the encapsulation lasted 3-4 weeks, during which voltage transients (VTs) increased and charge storage capacity (CSC) decreased.
  • The findings suggest that the changes in VTs and CSC are linked to the healing process, and that traditional methods may underestimate the limits of charge injection during encapsulation.
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