Publications by authors named "N Iu Kasaganova"

Concentration of trace levels of copper, iron and selenium as well as activity of superoxide dismutase and content of ceruloplasmin and transferrin were studied in blood serum of 70 patients with defects and deformations of cervicofacial region before and after surgical plastic operations approximately similar in their size and the rate of traumatic injury. Alterations in content of the trace elements as well as in content and activity of the metalloenzymes, observed during pyo-inflammatory complications, were considerably distinct from these patterns detected in noncomplicated wound inflammation; the patterns studied may be used for prognostic purposes.

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Surgical interventions on soft tissues of the face and neck induce a nonspecific reaction of the body, activating the nonenzymic antioxidative system for regulation of lipid peroxidation processes. The activity of this system is suppressed in pyoinflammatory complications of postoperative wounds, whereas the level of free-radical processes persists high and impaired regulation of lipid peroxidation results in prolongation of all phases of the wound process and in longer wound healing. At the same time a reduction of ceruloplasmin and transferrin levels in the first 24 hrs after surgery may be used as diagnostic test in postoperative pyoinflammatory complications.

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