Publications by authors named "N Iu Avvakumova"
Article Synopsis
- MicroRNAs (miRNAs) are crucial for regulating gene expression, and their dysregulation is frequently linked to cancer, particularly melanoma, the deadliest skin cancer.
- This study focused on identifying significant miRNA biomarkers for advanced melanoma and evaluating their potential in diagnostics through blood plasma analysis, finding notable differences between melanoma patients and healthy controls.
- Additionally, the research explored the efficacy of humic substances and chitosan to lower specific miRNA markers associated with melanoma, indicating their potential as therapeutic agents.
The effect of individual components of humic substances of peloid on free radical oxidation processes has been investigated under conditions of oxidative stress induced in albino rats. Biological activity of peloids was determined using such parameters as the general antioxidant activity, activity superoxide dismutases, catalases and glutathione peroxidases on the third and tenth day of the experiment. Results indicate that the state of oxidative stress can be corrected on the third day of the experiment.
View Article and Find Full Text PDFIntroduction: Chronic gastritis with syndrome, functional dyspepsia (SFD) is one of the most pressing problems in medicine. Certain scientific and practical interest is the elucidation of the frequency and clinical manifestations of functional dyspepsia in patients hospitalized in the gastroenterology department YAGKB and frequency combinations of chronic gastritis (including H. pylori) with functional dyspepsia.
View Article and Find Full Text PDF[Epidemiologic characteristic of Legionnaires' disease outbreak in town Verkhnyaya Pyshma].
Zh Mikrobiol Epidemiol Immunobiol
June 2008
Materials of investigation of Legionnaires' disease outbreak in town Verkhnyaya Pyshma (Sverdlovsk region) are presented. Features of epidemic process during this outbreak were reflected, its epidemiologic characteristics were described. Effectiveness of timely antiepidemic measures directed at elimination of main factor of infection's transmissibility was shown.
View Article and Find Full Text PDF[Epidemiologic versions in investigation of Legionnaires' disease outbreak in town Verkhnyaya Pyshma].
Zh Mikrobiol Epidemiol Immunobiol
June 2008
Materials of investigation of Legionnaires' disease outbreak in one of the town of Sverdlovsk region in summer 2007 are presented. Outbreak arose in situation of epidemiologic welfare on majority of registered infectious diseases. Epidemiologic diagnostics of the outbreak has been performed in maximal shorttime interval, during which it was necessary to investigate variety of miscellaneous versions.
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