Publications by authors named "N Ichihara"

Article Synopsis
  • * The study identified seasonal trends in adverse events like dehydration, cerebral infarction, urinary tract infections, and ketoacidosis linked to six SGLT2 inhibitors prescribed in Japan.
  • * Findings showed dehydration-related issues were most common in summer and winter, with a peak for cerebral infarction in February, suggesting healthcare professionals should be vigilant about dehydration risks throughout the year.
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Amphotericin B deoxycholate (AMPH-B) is a polyene macrolide with antifungal activity. Liposomal AMPH-B (L-AMB) was developed to reduce side effects while maintaining antifungal activity. This study was aimed at evaluating and comparing the adverse event profiles of AMPH-B and L-AMB using a spontaneous reporting system.

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Article Synopsis
  • * The researchers utilized a self-organizing map (SOM) and decision tree analysis to differentiate between 31 antipsychotics, revealing detailed NMS profiles beyond the usual classifications of typical and atypical antipsychotics.
  • * The study analyzed 887,704 reports from the Japanese Adverse Drug Event Report database, providing valuable insights on NMS occurrences with specific antipsychotics to help healthcare providers better manage schizophrenia treatment.
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Three-dimensional (3D)-printed models of bones are a convenient and durable alternative to real bone specimens, and they have been used in anatomy laboratories. It is necessary to identify the precise advantages of 3D-printed models from all perspectives; not only the improvement in students' knowledge of anatomy but also the students' assessment of such models. Here, students of veterinary medicine and animal science evaluated the reproducibility and effectiveness of 3D-printed models as a learning tool by completing our questionnaires, with a focus on their understanding of the skull-morphological differences among dog breeds.

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Background: Selective sinus replacement seems a reasonable option in cases requiring replacement of one or two sinuses of Valsalva, especially with acute aortic dissection and high bleeding risk.

Methods: Six patients (average age 58±17 years;five males) underwent selective replacement of the right sinus of Valsalva with right coronary artery bypass grafting (n=5) in 2015-2023. Five patients developed acute aortic dissection and one developed aneurysm of the right sinus of Valsalva.

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