Publications by authors named "N I VINOGRADOVA"
Article Synopsis
- A study aimed to evaluate mortality risks in patients with chronic heart failure (CHF) following hospitalization for acute decompensated heart failure (ADHF) over five years, comparing specialized care to general care.
- It involved 942 patients divided into two groups: one receiving outpatient follow-up at a specialized center and the other at local clinics, with mortality rates analyzed based on various causes.
- Results showed that specialized follow-up significantly reduced all-cause death (32.3% vs. 53.5%), cardiovascular death, and death from recurrent ADHF risks compared to general follow-up, indicating better outcomes with specialized care.
Article Synopsis
- The study aimed to identify why patients with chronic heart failure (CHF) in Russia have a poor prognosis, using data from various population samples and medical records over several years.
- It established the prevalence of CHF in the Russian population, finding that 8.2% of individuals meet soft criteria for CHF, while 3.1% met strict criteria, with significant influences from conditions like hypertension and ischemic heart disease.
- The prognosis for these patients is grim, with over half dying within four years after acute decompensated heart failure (ADHF), and most patients with severe CHF not surviving beyond ten years, primarily due to inadequate medication use and poor patient follow-up.
Article Synopsis
- Autism spectrum disorders (ASDs) are neurodevelopmental disorders marked by social interaction challenges and repetitive behaviors, often seen alongside other conditions like intellectual disability and ADHD.
- Pathogenic variants in the CHD8 gene are among the identified genetic causes of ASDs, influencing brain development and cellular growth during embryogenesis.
- A study found significant CHD8 variants in 6 children and 1 adult, revealing unusual symptoms like hepatomegaly and cardiovascular issues, indicating the need for further research on CHD8's complex interactions with other proteins.
The burden of heart failure (HF) has been increasing worldwide in recent decades. Early diagnosis of HF based on the outpatient measurement of natriuretic peptide (NP) concentration will allow timely initiation of the treatment and reducing the incidence of adverse outcomes in HF. Unfortunately, the frequency of NP testing remains low worldwide.
View Article and Find Full Text PDFA meeting of Interdisciplinary Expert Panel with leading specialists in the field of orthopedics/traumatology, surgery, rheumatology, and neurology was held in Moscow on February 10, 2023. The purpose of the meeting was to discuss the current status of local injection therapy (LIT) in Russia and the rationale behind the use of collagen-based products for various musculoskeletal disorders. The experts considered the following issues: (1) General contraindications to the use of medical products based on tropocollagen as well as an algorithm for actions in case of adverse events; (2) Guidelines regarding LIT in general and LIT using tropocollagen in particular, including in combination with other LIT products; (3) Particular indications and approaches to the treatment of patients with abnormal changes in appendicular joints and spine with damage to both intra-articular structures and periarticular soft tissue.
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