[Iron deficiency syndromes associated with diseases of the gastrointestinal tract: state-of-the-art and new prospects for treatment].

Organs of the gastrointestinal tract (GIT) are essential for iron metabolism and hematopoiesis regulation. Iron deficiency is accompanied by a large number of diseases of GIT. The article discusses the problem of diagnosis and treatment of anemia, It describes mechanisms of development of anemia associated with bleeding, malabsorption, and chronic inflammation.

[Cryoglobulinemia in a case of multiple myeloma associated with viral hepatitis B].

Cryoglobulinemia is a biochemical disorder accompanying many infectious, systemic, and lymphoproliferative conditions. Cryoglobulins are proteins capable of reversible precipitation or gel formation at temperatures below 37 degrees C. There are 3 types of cryoglobulins depending on the type of immunoglobulins in their composition; hence, three types of cryoglobulinemia occurring in different diseases.

[Iron deficiency anemia. Modern diagnostic and treatment strategy. Criteria for therapeutic efficacy].

Modern views of epidemiology, etiology and pathogenesis of iron deficiency anemia are considered. Mechanisms of iron metabolism regulation are described based on the most important literature data and the results of the authors' research. The authors present their own and literature clinical experience of using iron-containing drugs with reference to the existing recommendations on the treatment of iron deficiency anemia.

[The laboratory evidences of chronic disease impact on the development of anemia under female reproductive system pathology].

The study sample included 170 patients with gynecological diseases, 5 patients with persistent anemia due to systematic blood disorder, 14 healthy patients. The decrease of hemoglobin level lower than 110 g/l is established in 25.7% gynecologic patients and most frequently in those with hysteromyoma.

[New capabilities for diagnosis of iron-deficiency anemia by computer morphometry of reticulocytes].

With the advent of new cytological techniques, such as computer morphometry, the problems in the study of the structure of reticulocytes that characterize insignificant changes in the parameters of erythroid population functioning in the bone marrow in response to altered hemoglobin synthesis in patients with iron-deficiency anemia (IDA) become topical. The changes in peripheral blood reticulocytes in IDA determine those in red blood cells and may be a reliable differential diagnostic tool to identify IDA.