Hepatic status was studied in 7 HIV-infected patients at the stage of generalized lymphadenopathy. Intravital needle biopsy obtained from the livers characterizes the latter as enlarged, showing signs of protein-synthesis dysfunction, morphological evidence of mild cytolysis, cholestasis, moderate mesenchymal-inflammatory syndrome. The study of autopsy specimens obtained from hepatic tissue of the woman who had died of AIDS disclosed more advanced lesions: hepatocytes dystrophy, intralobular and periportal infiltration.
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