Parametric Sequential Method for MRI-Based Wall Shear Stress Quantification.

Wall shear stress (WSS) has been suggested as a potential biomarker in various cardiovascular diseases and it can be estimated from phase-contrast Magnetic Resonance Imaging (PC-MRI) velocity measurements. We present a parametric sequential method for MRI-based WSS quantification consisting of a geometry identification and a subsequent approximation of the velocity field. This work focuses on its validation, investigating well controlled high-resolution in vitro measurements of turbulent stationary flows and physiological pulsatile flows in phantoms.

MR-based wall shear stress measurements in fully developed turbulent flow using the Clauser plot method.

In arterial blood flow wall shear stress (WSS) quantifies the frictional force that flowing blood exerts on a vessel wall. WSS can be directly estimated from phase-contrast (PC) MR velocity measurements and has been suggested as a biomarker in cardio-vascular diseases. We present and investigate the application of the Clauser plot method for estimating WSS in fully developed turbulent stationary flow using PC velocity measurements.