[Circulating immune complexes and immunoglobulins A, M and G in the mother-fetus system in normal pregnancy and gestosis].

Circulating immune complexes (CIC) and immunoglobulins A, M, and G were measured in the maternal peripheral blood, mixed umbilical blood, and amniotic fluid in women with normal pregnancy and gestosis. CIC concentrations in the examined fluids did not surpass the levels typical of healthy donors. Maternal blood CIC levels were higher in gestosis than in normal pregnancy, and CIC levels in the umbilical blood and amniotic fluid were always lower than in maternal blood serum.

[Immunological properties of the amniotic fluid in physiological pregnancy and gestoses].

Immunologic analysis of the amniotic fluid included measurements of immunoglobulins A and M, circulating immune complexes, rheumatoid and antinuclear factors, immunophoresis and electrophoresis, and tests for the presence of donor lymphocytes, Changed immunologic parameters of the amniotic fluid indicate a complicated course of pregnancy, development of gestosis among other things. Basing on their findings, the authors suggest that gestosis involve dysfunction of the adaptive mechanisms, that may result from disordered interactions of the immunity system components.

[Serum trophoblastic beta 1-glycoprotein and alpha fetoprotein levels in physiological pregnancy].

Measurements of maternal blood serum trophoblastic beta 1-glycoprotein and alpha-fetoprotein, carried out over the course of normal pregnancy, have demonstrated a progressive increase of trophoblastic beta 1-glycoprotein up to the 36th week, though its level somewhat reduced during the 28th and 32nd weeks. After week 39 the level of this protein in maternal blood serum progressively lowered. alpha-Fetoprotein level was increasing over the course of pregnancy as long as up to the 32nd-34th weeks, then lowering the rest of the term up to delivery.