Tertiary Structures of Haseki Tick Virus Nonstructural Proteins Are Similar to Those of .

Currently, a large number of novel tick-borne viruses potentially pathogenic to humans are discovered. Studying many of them by classical methods of virology is difficult due to the absence of live viral particles or a sufficient amount of their genetic material. In this case, the use of modern methods of bioinformatics and synthetic and structural biology can help.

STATE OF ORGANIZATION OF PROVIDING ONCOLOGICAL MEDICAL CARE TO THE POPULATION OF UKRAINE.

Objective: Aim: The purpose of this work is to study the state of organizational factors in the provision of oncology care to the population of Ukraine and to determine the needs of the population in oncology care.

Patients And Methods: Materials and Methods: The following materials were used in study: a report on diseases of malignant neoplasms; report on medical personnel; report on contingents of patients with malignant neoplasms. The used methods were: bibliosemantic, content analysis, analytical, statistical and graphical methods.

[The comparative effectiveness of the application of various methods for electrical muscle stimulation in the patients presenting with juvenile cerebral palsy].

We studied the clinical effectiveness of rehabilitation of 168 patients presenting with juvenile cerebral palsy in the form of spastic diplegia who received the comprehensive rehabilitative treatment including therapeutic physical exercises, paraffin applications, general hydromassage baths, manual massage and electrical stimulation of weakened muscles with the use of the following devices: for group 1 of the patients (n=38), for group 2 (n=43), for group 3 (n=45), and for group 4 (n=38). The study yielded the significantly higher scores in the test for groups 1,2, and 3 compared with group 4 (p<0.05).

[Effect of the Na+, K(+)-ATPase modulation in neurons of the medulla oblongata on hemodynamic effects in spontaneously hypertensive rats].

The study was conducted in normotensive and spontaneously hypertensive rats anesthetized with urethane (1600 mg/kg of animal weight, intraperitoneally). It has been shown that in normotensive rats, injections of a specific inhibitor of Na+, K(+)-ATPase ouabain (10(-8)-10(-5) mol/l) in the populations of the neurons within nucleus of the solitary tract (NTS), paramedian reticular nucleus (PMn) and lateral reticular nucleus (LRN) were accompanied by the development of the hypertensive responses in a dose-dependent fashion. These data suggest that Na+, K(+)-ATPase of the neuron somatic membranes in the medullary cardiovascular nuclei is involved in neural control of the cardiovascular function, and its inhibition by microinjections of ouabain promotes the development of hypertension.