PfEMP1: an antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum.

The deadliest form of human malaria is caused by the protozoan parasite Plasmodium falciparum affecting millions worldwide every year. P. falciparum virulence is attributed to its ability to evade the human immune system by modifying infected host red blood cells to adhere to the vascular endothelium and to undergo antigenic variation.

Nucleoli and AgNORs in Hodgkin's disease.

Aim: To evaluate the morphofunctional characteristics of lymph node cells from patients with Hodgkin's disease by measuring silver stained nucleolar organiser regions (AgNORs).

Methods: Nucleoli in Hodgkin's and Reed-Sternberg (HRS) cells, lymphocytes and prolymphocytes were investigated in cytological smears and histological sections of lymph nodes from 32 patients with Hodgkin's disease, and from 34 patients with reactive lymphadenopathy. According to the Rye histological classification of Hodgkin's disease, three cases were the lymphocyte predominant (LP) type, 14 the nodular sclerosing (NS) type, and 15 the mixed cellularity (MC) type.