[Combined examination of the hypophysis-adrenal cortex system in breast cancer].

A multimodality radioimmunological and clinicobiochemical study showed an increase in the hydrocortisone level and a decrease in the ACTH level in breast cancer patients. Stage I, following radical mastectomy (RM). A simultaneous increase in the hydrocortisone, ACTH and aldosterone level after RM, chemotherapy, hormone therapy was noted in all patients with breast cancer, Stages II and III, with initially lowered hydrocortisone and aldosterone levels and an elevated ACTH level.