[Activity of the anthelmintic agent trichlorophen on the models of human helminthiasis].

Trials of trichlorophen have shown its high efficacy on models of cestode infections: hymenolepiasis (at the adult and cysticercoid stages of development on three types of animals: outbred albino mice, albino rats and golden hamsters), preimaginal echinococciasis alveolaris, larval alveolar echinococciasis (at the early stage of development of the parasite in experiments on cotton rats). The high nematodical activity of trichlorophen was first found on models of trichocephaliasis in DBA/2y mice, nippostrongyloidiasis (in in vitro experiments), and aspiculuriasis in outbred mice. The agent proved to be ineffective at the tissue developmental stage of Hymenolepsis nana (H.

[A comparative study of the efficacy of medamine, albendazole and embovin in models of syphaciasis and aspiculariasis].

The study covers the study of three antinematodal agents: the original national drug medamine with albendazole and embovin (pyrathel pamoate), which have been reproduced at the E. I. Martsinovskiĭ Institute of Medical Parasitology and Tropical Medicine, with murine Syphacia obvelata and Aspiculuris tetraptera infection models.

[A luminescence microscopy method for studying organ function in Aspiculuris tetraptera (Schulz, 1924)].

The paper proposes the rapid technique for examining the luminescence pattern of individual systems and organs in the murine parasite Aspiculuris tetraptera. The luminescence pattern of the parasite was studied after fluorochrome-plating with rhodamine 6G, rhodamine C, coryphosphine, sodium fluorescein, acridine orange which was found to be the optimum fluorochrome. This technique is to be used in the evaluation of the effects of chemopharmaceuticals on the parasite.

[The efficacy of a new Russian preparation metiazol in experimental aspiculariasis in mice].

The efficacy of metiasole, a new Russian analog of albendasole, reproduced at the E. I. Martsinovskiĭ Institute of Medical Parasitology and Tropical Medicine, was studied in mice with Aspiculuris tetraptera invasion.

[Clinico-economical effectiveness of conservative and surgical treatment of duodenal ulcer (results of 5-year study)].

The comparative assessment of the clinico-economical efficiency of the conservative and surgical treatment of the patients with duodenal ulcer disease was carried out. Direct expenses for surgical treatment were 2.5-fold higher than those for conservative treatment.