Publications by authors named "N I Komova"

Uncontrolled use of pesticides in agriculture leads to negative consequences for the environment, as well as for human and animal health. Therefore, timely detection of pesticides will allow application of measures to eliminate the excess of maximum residue limits and reduce possible negative consequences in advance. Common methods of pesticide analysis suffer from high costs, and are time consuming, and labor intensive.

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When developing immunochemical test systems, it is necessary to obtain specific antibodies. Their quality depends, among other things, on the immunogen used. When preparing hapten-protein conjugates to obtain antibodies for low-molecular-weight compounds, the key factors are the structure of the hapten itself, the presence of a spacer, the size of the carrier protein and the degree of its modification by hapten molecules.

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Article Synopsis
  • - A new bimetallic nanorod structure was created using a Raman reporter to enhance the detection of the insecticide fipronil in a specific immunoassay technique called SERS-LFIA.
  • - This method achieved a very low detection limit for fipronil at 4.6 pg/mL and is the first of its kind specifically for this insecticide, demonstrating effectiveness in real food samples like cucumber and apple juice.
  • - The use of antibodies to functionalize the SERS nanotag offers a flexible approach for enhancing various lateral flow immunoassays, improving their overall performance.
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Contamination of the environment by technogenic endocrine disrupting compounds (EDCs) becomes serious threat to public health. To effectively prevent this threat, it is necessary to improve analytical methods for EDCs to ensure mass, fast and productive monitoring. In the given work, a dual lateral flow test (LFT) is developed in the first time for simultaneous immunodetection of bisphenol A and dimethyl phthalate, priority EDCs releasing from plastic and belonging to different chemical classes.

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The toxic effects of antimony pose risks to human health. Therefore, simple analytical techniques for its widescale monitoring in water sources are in demand. In this study, a sensitive microplate apta-enzyme assay for Sb detection was developed.

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