Publications by authors named "N I Khramenko"
A neural network model for predicting the effectiveness of treatment in patients with neovascular glaucoma associated with diabetes mellitus.
Rom J Ophthalmol
October 2024
Article Synopsis
- The study explores the effectiveness of neural networks in predicting treatment outcomes for diabetic neovascular glaucoma (NVG), focusing on intraocular pressure, inflammation, and blood circulation indicators.
- The research involves a cohort of 127 NVG patients and a control group, using specific preoperative indices to analyze the impact on treatment success after transscleral cyclophotocoagulation (TSC CPC).
- The neural network model developed highlighted the significance of the systemic inflammation response index (SIRI), rheographic coefficient (RQ), and systemic immune-inflammation index (SII) in predicting treatment efficacy, demonstrating high sensitivity but lower specificity.
Features of hemodynamic and immunological parameters in patients with recurrent uveitis complicated by hypertension, Fuchs heterochromic uveitis and Posner-Schlossman syndrome.
Rom J Ophthalmol
April 2023
Uveitis is a disease that manifests with increased vascular permeability and occlusion, with some ischemia and inflammatory mediators. It is characterized by a wide range of pathological processes, including inflammation, increased vascular permeability and occlusion, local ischemia and cell alteration by inflammatory mediators, and is characterized by the presence of complications. To study the state of ocular hemodynamics by rheoophthalmography, as well as the immune status in patients with idiopathic recurrent anterior uveitis complicated by intraocular hypertension, Fuchs heterochromic uveitis, Posner-Schlossman syndrome, during the relapse period.
View Article and Find Full Text PDFImmunity status and expression of molecular markers (ICAM-1, CD5, CD25, CD95) on lymphocytes of patients with recurrent anterior uveitis complicated by macular edema.
Graefes Arch Clin Exp Ophthalmol
May 2023
Background: Treatment of macular edema in uveitis is a key goal of treatment, because this complication remains a potential therapeutic problem for specialists.
Material And Methods: Examination was carried out in 1-2 groups - 50 persons with uncomplicated recurrent anterior uveitis (AU) in the stage of relapse or remission - and 3-4 groups - 26 persons with recurrent AU complicated by uveitic macular edema (UME) in the stage of relapse or remission of AU. Control group - 27 healthy volunteers.
There were concluded our results of animal experimental investigation and clinical observation of the quercetin-containing preparation corvitin (C) in primary glaucoma treatment. On the model of disease it is shown for rabbit, that introduction of 0.5 ml 2 % C as factious instillation into the eye a basely decreased eye blood flow was increased twice, mionectic at glaucoma eye hydrodynamics was normalized : the outflow of liquid increased on 58 %, inflow - on 52 %, intraocular pressure went down on 14%.
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