Publications by authors named "N I Gavin"

Purpose: Patients receiving treatment for solid tumours and haematological malignancies, among other acute and chronic health conditions, are highly dependent upon central venous access devices (CVADs) for administering chemotherapy and other complex therapies; thus, CVADs can meaningfully impact their health outcomes and experiences. This systematic review aimed to identify and critique patient-reported outcome measure (PROM) and patient-reported experience measure (PREM) instruments related to CVADs.

Methods: A systematic review was undertaken, commencing with an electronic search of health databases (April 2022).

View Article and Find Full Text PDF

Background: Accurate medical coding is essential for clinical and administrative purposes but complicated, time-consuming, and biased. This study compares Retrieval-Augmented Generation (RAG)-enhanced LLMs to provider-assigned codes in producing ICD-10-CM codes from emergency department (ED) clinical records.

Methods: Retrospective cohort study using 500 ED visits randomly selected from the Mount Sinai Health System between January and April 2024.

View Article and Find Full Text PDF
Article Synopsis
  • Scar tissue formation is a critical part of wound healing but can disrupt tissue function, particularly in cases like uterine scarring from cesarean sections.
  • The research focused on how deep uterine scars contribute to a condition called placenta accreta spectrum (PAS), where invasive cells can lead to serious complications during pregnancy.
  • The study found that scar tissue activates the mechanosensitive ion channel, Piezo1, which triggers inflammatory pathways and draws invasive cells towards the scar, highlighting how scar mechanics can disturb normal tissue interactions and potentially relate to cancer spread.
View Article and Find Full Text PDF

Background: Monoclonal antibodies are widely used anticancer therapies. Increasing demand for ambulatory care necessitates exploration of efficiency measures.

Objectives: The primary objective was to evaluate the impacts on chair time and associated cost of priming IV administration sets with a bolus of the prescribed monoclonal antibody drugs.

View Article and Find Full Text PDF

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the relative effectiveness and vascular access device (VAD)-related complications of VADs in people requiring prolonged systemic anti-cancer treatment.

View Article and Find Full Text PDF