HEMOPERFUSION USING THE LPS-SELECTIVE MESOPOROUS POLYMERIC ADSORBENT IN SEPTIC SHOCK: A MULTICENTER RANDOMIZED CLINICAL TRIAL.

Extracorporeal hemoperfusion (EHP) may improve the course and outcomes of patients with septic shock by targeting cytokines or bacterial endotoxins (lipopolysaccharide [LPS]). Here, we present the results of a multicenter randomized controlled trial ( clinicaltrials.gov/ct2/show/NCT04827407 ) to assess the efficiency and safety of Efferon LPS hemoperfusion cartridges engineered for multimodal targeting LPS, host-derived cytokine, and damage-associated molecule pattern molecules.

[Features of the course of non-ST elevation myocardial infarction in patients with a history of COVID-19].

Aim      To study the clinical course of non-ST segment elevation myocardial infarction (NSTEMI) in hospitalized patients after COVID-19 and to evaluate the effect of baseline characteristics of patients on the risk of complications.Material and methods  The study included 209 patients with NSTEMI; 104 of them had had COVID-19. The course of myocardial infarction (MI) was analyzed at the hospital stage, including evaluation of the incidence rate of complications (fatal outcome, recurrent MI, life-threatening arrhythmias and conduction disorders, pulmonary edema, cardiogenic shock, ischemic stroke, gastrointestinal bleeding).

Six-Month Quality of Life in COVID-19 Intensive Care Unit Survivors.

Objectives: Because there is increasing evidence of serious deterioration in long-term quality of life (QoL) in coronavirus 2019 (COVID-19) intensive care unit (ICU) survivors, the authors identified predictors of poor quality of life in these patients.

Design: Prospective cohort study.

Setting: Research hospital repurposed into a COVID-19 center.

Use of an extracorporeal arteriovenous tubing loop to measure cardiac output in intensive care unit patients by ultrasound velocity dilution.

Thermodilution cardiac output (CO) measurement requires heart catheterization and is known as a risk factor. The existing cannula in the radial artery in intensive care unit (ICU) patients can be used to measure CO by ultrasound dilution (COus). An arteriovenous shunt between the radial artery and cubital vein was created using a 25 cm tubing loop.

[The determination of cardiac output by the dilution of ultrasonic blood density].

The authors propose assessing cardiac output (CO) by diluting the blood ultrasonic properties. For measuring CO, the peripheral artery and vein were connected with a catheter, and ultrasonic flowmetric pickup was attached to the shunt. Indicator (0.