Early Screening for Risks of Bipolar Disorder at the Preclinical Stage.

Introduction: Bipolar disorder (BD) is characterized by a high rate of prevalence in the general population varying from 0.6% to 5.84% (Yildiz 2015).

[Clinical features of depressive episode with onset in adolescence and the risk of bipolar depression].

Aim: To study clinical features of depressive episode with the onset in late adolescence associated with the risk of bipolar affective disorder (BAD).

Material And Methods: Forty patients with BAD (ICD-10 F31), who experienced depressive state at the age of 15-18 years corresponding to the diagnostic criteria of 'Depressive episode' (F32), were examined. The duration of follow-up was from 3 to 5 years.