Publications by authors named "N Hoyeau-Idrissi"

Background: Familial Mediterranean Fever (FMF) is the most frequent monogenic autoinflammatory disease (AID). Some patients have persistent symptoms despite colchicine intake. Mast cells (MC) are innate immune cells involved in inflammatory conditions including AID.

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Article Synopsis
  • - Mastocytosis is a disease marked by an abnormal buildup of mast cells in various organs, often leading to gastrointestinal issues, which had not been extensively described before in the literature.
  • - A study compared the gastrointestinal symptoms of 83 patients with mastocytosis to those of 83 healthy individuals, revealing significantly higher rates of issues like bloating, abdominal pain, nausea, and diarrhea in the mastocytosis group.
  • - The findings indicated that while gastrointestinal symptoms are common in mastocytosis patients, they do not directly correlate with the specific histologic changes observed, making diagnosis challenging as symptoms can mimic conditions like irritable bowel syndrome.
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Background: Esophageal xanthoma is a very rare lesion which can be incidentally discovered during endoscopy. Only eleven cases have been reported, including ours.

Case Reports: We present two new cases of esophageal xanthoma localized in the lower esophagus in a 56-year-old woman and a 62-year-old man.

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Aim: To evaluate whether crypt abscesses from inflammatory bowel disease (IBD) patients contain bacteria and to establish their nature.

Methods: We studied 17 ulcerative colitis patients, 11 Crohn's disease patients, 7 patients with acute self-limited colitis (ASLC) and normal colonic biopsies from 5 subjects who underwent colonoscopy for colon cancer screening. A fluorescent in situ hybridization technique was applied to colonic biopsies to assess the microbiota composition of the crypts and crypt abscesses.

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