The thyroid gland, located at the base of the neck, regulates metabolism and hormone balance through hormones like T4 and T3, which are essential for growth, neurological development, and energy production. Thyroid diseases affect 10% of the global population, making accurate and up-to-date information on surgical interventions and advancements crucial for improving clinical outcomes. Thyroid gland surgery is a dynamic field that has experienced remarkable advances in diagnosis, surgical techniques, and postoperative management.
View Article and Find Full Text PDFMulti-heme cytochromes (MHCs), together with accessory proteins like porins and periplasmic cytochromes, enable microbes to transport electrons between the cytoplasmic membrane and extracellular substrates (e.g., minerals, electrodes, other cells).
View Article and Find Full Text PDFTraditionally, surveillance programs for food products and food processing environments have focused on targeted pathogens and resistance genes. Recent advances in high throughput sequencing allow for more comprehensive and untargeted monitoring. This study assessed the microbiome and resistome in a poultry burger processing line using culturing techniques and whole metagenomic sequencing (WMS).
View Article and Find Full Text PDFThe coordination of enzymes and regulatory proteins for eukaryotic DNA replication and repair is largely achieved by Proliferating Cell Nuclear Antigen (PCNA), a toroidal homotrimeric protein that embraces the DNA duplex. Many proteins bind PCNA through a conserved sequence known as the PCNA interacting protein motif (PIP). PCNA is further regulated by different post-translational modifications.
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