Rapid Development and Rupture of an Infected Intracranial Aneurysm Caused by Streptococcus salivarius Meningitis: A Case Report.

The clinical manifestation of intracranial mycotic aneurysms (ICMAs), which are rare but carry high risks of rupture and early mortality, remains poorly understood. We present a case of an ICMA that rapidly developed and ruptured after the diagnosis of meningitis caused by (), which rarely causes bacterial meningitis. A 54-year-old man presented with a headache that worsened on coughing, without altered consciousness or vomiting.

Expansion of the MIRAgel Scleral Buckle With Findings Resembling Necrotizing Scleritis: A Case Report.

MIRAgel is a hydrogel buckle material that was widely used for scleral implantation surgery in the past. However, postoperative complications such as conjunctival hyperemia and impaired eye movements were reported due to postoperative expansion of the MIRAgel buckle. In addition, damage to the sclera due to hydrolysis of the MIRAgel buckle has been reported.

Drug-resistant F V600E-mutant recurrent pleomorphic xanthoastrocytoma, CNS WHO Grade 3 successfully resolved with incidental discontinuation of combined BRAF and MEK inhibitor therapy.

Background: Combination therapy with BRAF and MEK inhibitor holds promise for treating gliomas harboring the V600E mutation; however, the development of acquired resistance remains a challenge.

Case Description: We describe a case of repeated recurrent mutant pleomorphic xanthoastrocytoma (central nervous system World Health Organization grade 3) treated with combination therapy with BRAF and MEK inhibitor. The patient received dabrafenib (BRAF inhibitor) and trametinib (MEK inhibitor); however, she developed resistance to the combination therapy.

Impact of urinary culture on diagnosis and treatment strategy after empiric therapy in febrile neutropenic patients.

Aim: Febrile neutropenia (FN) is treated by a broad-spectrum antimicrobial. Subsequent antimicrobial therapy depends on identifying the source of the infection. Although urinary tract infections (UTIs) are common and urine culture (UC) is a valuable diagnostic tool, uncertainties remain about the specific indications for conducting UC in FN.