Air emissions from the shipbuilding process.

Seaborn trade has a share of about 80 % in global supply chains and is responsible for approximately 10 % of global carbon emissions. This is why the environmental impact of ships and the shipbuilding process matter. Despite that, this topic is addressed rather sparsely in the present literature body.

Missense variants in the TRPM7 α-kinase domain are associated with recurrent pediatric acute liver failure.

Background: Pediatric acute liver failure (PALF) is a rare and life-threatening condition. In up to 50% of PALF cases, the underlying etiology remains unknown during routine clinical testing. This lack of knowledge complicates clinical management and liver transplantation decisions.

Life-cycle cost assessment of hull protection technologies considering their effect on the environmental friendliness of fishing vessels.

Biofouling represents a global challenge for the maritime industry, affecting vessel performance and environmental footprint. This paper analyses various antifouling technologies to reduce the vessel's environmental impact and its operating costs by reduced fuel consumption and less frequent dry-docking. It evaluates both passive and active technologies - passive referring to antifouling coatings and active involving systems that continuously prevent biofouling using energy.

Hereditary tyrosinaemia type 1 in the absence of succinylacetone: 4-oxo 6-hydroxyhepanoate (4OHHA), a putative diagnostic biomarker.

Hereditary tyrosinemia type 1 (HT1) is a rare metabolic disease resulting in acute liver failure in early infancy, hypophosphataemic rickets, neurological crises, liver cirrhosis and risk of hepatocellular carcinoma later on in life. It is caused by the deficiency of the enzyme fumarylacetoacetate hydrolase which is involved in the terminal step of the catabolic pathway of tyrosine. Diagnosis is made through clinical suspicion supported by biochemical abnormalities that result from accumulation of upstream metabolites.