; PARAMETERS OF FIBRINOLYTIC AND ANTIFIBRINOLYTIC ACTIVITY IN PATIENTS WITH ALCOHOLIC LIVER CIRRHOSIS ASSOCIATED WITH ADIPOSITY.

The aim of study was to study the changes in the parameters of fibrinolytic and antifibrinolytic systems in patients with alcoholic liver cirrhosis (ALC), depending on the combination with adiposity and decompensation of the disease.; The subject of the study were 104 patients with ALC, 16 women and 88 men aged 34 to 65 years; among them there were 66 patients with ALC associated with adiposity (group I), 38 patients with ALC (group II). Control subjects were 20 practically healthy volunteers (4 women and 16 men).

[HEPATOCELLULAR TOXICITY IN THE BACKGROUND OF AMIODARON-INDUCED THYROID DYSFUNCTION IN PATIENTS WITH ATRIAL FIBRILLATION].

The purpose of the work was to establish the frequency and conditions in which structural and functional changes of the liver might occur in case of long-term amiodarone use, depending on thyroid dysfunction. The study included 80 patients with cardiosclerosis with atrial fibrillation (AF). The patients were assigned to: group I (n=60) - received amiodarone at a maintenance dose for one year (on background of basic therapy); control group (CG) - patients (n=20) who received on the background of basic therapy digoxin and bisoprolol.

[The role of growth factors in pathogenesis of hepatic lesions in patients with metabolic syndrome and chronic non-calculous cholecystitis].

Clinical examination and biochemical studies revealed hepatic functional disorders in 30 (93.75 +/- 4.28%) of 32 patients with metabolic syndrome (MS) and chronic non-calculous cholecystitis (NCC) and only in 3 (13.

[Diagnostic value of soluble interleukin-2 receptors in patients with alcoholic liver disease].

The medical inspection of the blood samples of 88 patients with alcoholic liver disease has revealed an increase in number of soluble receptors to interleukin-2, which was associated with the intensity of cytolytic and mesenchymal-inflammatory syndromes and in patients with cirrhosis of liver--the development of hepatocellular insufficiency.

[Apoptosis of peripheral blood lymphocytes in patients with chronic viral hepatitis].

The examined 68 patients with chronic viral hepatitis (CVH) demonstrated a high Fas/APO-1 (CD95) expression on the peripheral blood lymphocytes. It correlated with the serum level of the tumor necrosis factor alpha (TNF alpha). The above findings suggest to us the implication of apoptosis in CVH pathogenesis.