Combined fractional CO laser with dimethyl sulfoxide (DMSO) 50% versus fractional CO Laser alone in the treatment of macular amyloidosis: clinical and histopathological assessment.

Background: Macular amyloidosis (MA) could be of cosmetic concern with a significant psychological impact for patients, and its treatment is challenging.

Aim Of The Work: To compare the efficacy and safety of combined fractional CO laser with dimethyl sulfoxide (DMSO) 50% versus fractional CO laser alone in the treatment of macular amyloidosis.

Patients And Methods: Twenty patients with macular amyloidosis were treated with monthly session of fractional CO laser only in one side of the lesion (area A), and fractional laser followed by application of DMSO 50% solution in the other side of the lesion (area B).

Development of gallic acid loaded composite nanovesicles for the topical treatment of acne: optimization, characterization, and clinical investigation.

Gallic acid (GA) proved to produce desired effects topically in the treatment of acne, through its antibacterial, anti-inflammatory and antioxidant characteristics. In the current work, nanovesicular systems; aspasomes loaded with GA were prepared, and evaluated on and levels. Formulations were coated with chitosan due to its mucoadhesive properties.

Evaluation of microneedling depth of penetration in management of atrophic acne scars: a split-face comparative study.

Background: Microneedling is a technique of repeated puncturing or drilling of the skin to induce repair and collagen induction. There are many reported important factors determining the efficacy of microneedling treatment. The extent of injury needed to produce the desired effect in each condition is one of these important factors.