[Academised nursing in direct patient care-but how?].

Demographic change and the resulting increase in chronic diseases, rapid developments in medicine and digitization, and the increasing shortage of skilled workers pose challenges for the German healthcare system. A rethink in patient care is required. This means that new structures, areas of action, and responsibilities must be implemented for professional nursing.

[Disorientation and delirium assessment : A secondary analysis of a prospective, observational study].

Disorientation may present as a warning sign of developing delirium. The most commonly used delirium assessment tool in Germany, the Confusion Assessment Method for Intensive Care Unit (CAM-ICU), does not rate "disorientation", since intubated patients cannot communicate verbally. However, the majority of German ICU patients are not orally intubated, so they could be examined for their orientation.

Efficient semi-analytical simulation of elastic guided waves in cylinders subject to arbitrary non-symmetric loads.

In this paper, we present an approach to model the propagation of high-frequency elastic guided waves in solid or hollow cylinders. This formulation requires only discretization of the radial direction, whereas the circumferential direction is approximated via a truncated Fourier series, and the axial direction is described analytically. The model is extended to allow applying arbitrary non-symmetric loads f(r,θ) on the flat cylinder surface.

Identification of novel therapeutic targets for blocking acantholysis in pemphigus.

Background And Purpose: Pemphigus is caused by autoantibodies against desmoglein (Dsg) 1, Dsg3, and/or non-Dsg antigens. Pemphigus vulgaris (PV) is the most common manifestation of pemphigus, with painful erosions on mucous membranes. In most cases, blistering also occurs on the skin, leading to areas of extensive denudation.