Background/objective: Endoprostheses might fail due to complications such as implant loosening or periprosthetic infections. The surface topography of implant materials is known to influence osseointegration and attachment of pathogenic bacteria. Laser-Induced Periodic Surface Structures (LIPSS) can improve the surface topography of orthopedic implant materials.
View Article and Find Full Text PDFSafe and successful pain management in pregnant women requires an understanding of the normal physiologic changes of pregnancy. Some hemodynamic changes of labor and delivery are attenuated by effective epidural analgesia. The ideal analgesic agent for laboring parturients should produce a rapid onset of analgesia that lasts throughout labor without any adverse effect on the mother or fetus.
View Article and Find Full Text PDFBackground And Objectives: A combined bolus and continuous epidural infusion technique of opioid and bupivacaine mixture has been described, although no pharmacokinetic data for this technique exists. The study documents the plasma concentration profile of epidural alfentanil in parturients using this technique, and evaluates the fetal heart rate tracing for associated changes following opioid administration.
Methods: Twenty-four subjects were randomized to receive epidural alfentanil 500 micrograms in 10 mL 0.
Background And Objectives: This study examines the effect of epinephrine on the time to achieve a T4 sensory level when added to a hyperbaric bupivacaine-fentanyl mixture for spinal anesthesia.
Methods: Sixty-nine healthy parturients scheduled for elective cesarean delivery were randomly assigned to three groups. All patients were given 9 mg hyperbaric 0.