Optimization of the green synthesis of gold nanorods using aqueous extract of peeled sour guava as a source of antioxidants.

Obtaining gold nanorods (AuNRs) through biosynthesis is an alternative that replaces the traditional use of ascorbic acid with chemical compounds such as polyphenols, owing to their notable antioxidant properties. Therefore, we developed an AuNR biosynthesis method using an aqueous extract of sour guava (Psidium araca). Initially, a study was conducted to determine the antioxidant capacity of different parts of the fruit (pulp and peel) over 14 days.

The relationship between lead levels and reading acquisition in Spanish speakers, evidence from Uruguayan schoolers.

Unlabelled: Lead is a well-known neurotoxicant that continues to affect children´s cognition and behavior. Nevertheless, we still have little evidence on the consequences of lead exposure on reading abilities, particularly in languages other than English.

Objective: To investigate the cross-sectional association between blood lead levels (BLL), and pre-reading and reading abilities in first-grade children from Montevideo, Uruguay.

Automated ASPECTS Segmentation and Scoring Tool: a Method Tailored for a Colombian Telestroke Network.

To evaluate our two non-machine learning (non-ML)-based algorithmic approaches for detecting early ischemic infarcts on brain CT images of patients with acute ischemic stroke symptoms, tailored to our local population, to be incorporated in our telestroke software. One-hundred and thirteen acute stroke patients, excluding hemorrhagic, subacute, and chronic patients, with accessible brain CT images were divided into calibration and test sets. The gold standard was determined through consensus among three neuroradiologist.

Blood lead levels and math learning in first year of school: An association for concern.

Lead is a well-known neurotoxicant that continues to affect children's cognition and behavior. With the aim to examine the associations of lead exposure with math performance in children at the beginning of formal schooling, we conducted a cross-sectional study of first-grade students from 11 schools in Montevideo, Uruguay. Math abilities were assessed with tests from the Batería III Woodcock-Muñoz (Calculation, Math Facts Fluency, Applied Problems, Math Calculation Skills and Broad Maths).

B cell-targeted polylactic acid nanoparticles as platform for encapsulating jakinibs: potential therapeutic strategy for systemic lupus erythematosus.

B cells are pivotal in systemic lupus erythematosus and autoimmune disease pathogenesis. To address this, Nile Red-labeled polylactic acid nanoparticles (NR-PLA NPs) loaded with the JAK inhibitor baricitinib (BARI), specifically targeting JAK1 and JAK2 in B cells, were developed. Physicochemical characterization confirmed NP stability over 30 days.