Publications by authors named "N Gurel"
Introduction This study aimed to evaluate drug-drug interactions (DDIs) and their association with the quality of life in patients with hypertension. Materials and methods This cross-sectional study included 123 patients with hypertension. DDIs were evaluated using the Medscape Drug Interaction Checker Database (Medscape, New York, NY).
View Article and Find Full Text PDFImportance: Sham-controlled trials are needed to characterize the effect of hypoglossal nerve stimulation (HGNS) therapy on cardiovascular end points in patients with moderate-severe obstructive sleep apnea (OSA).
Objective: To determine the effect of therapeutic levels of HGNS, compared to sham levels, on blood pressure, sympathetic activity, and vascular function.
Design, Setting, And Participants: This double-blind, sham-controlled, randomized crossover therapy trial was conducted from 2018 to 2022 at 3 separate academic medical centers.
Article Synopsis
- Transcutaneous cervical vagus nerve stimulation (tcVNS) is explored as a treatment for stress-related psychiatric disorders, with ghrelin identified as a possible stress biomarker.
- A randomized double-blind study found that tcVNS lowers ghrelin levels significantly during and after stress-inducing tasks compared to a sham treatment.
- The study suggests that tcVNS helps regulate hormonal responses to stress, although there are limitations such as measurement timing and the stimulation focused only on the left vagus nerve.
Background: Posttraumatic stress disorder (PTSD) is associated with changes in multiple neurophysiological systems, including verbal declarative memory deficits. Vagus Nerve Stimulation (VNS) has been shown in preliminary studies to enhance function when paired with cognitive and motor tasks. The purpose of this study was to analyze the effect of transcutaneous cervical VNS (tcVNS) on attention, declarative and working memory in PTSD patients.
View Article and Find Full Text PDFNon-invasive continuous blood pressure monitoring remains elusive. There has been extensive research using the photoplethysmographic (PPG) waveform for blood pressure estimation, but improvements in accuracy are still needed before clinical use. Here we explored the use of an emerging technique, speckle contrast optical spectroscopy (SCOS), for blood pressure estimation.
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