Publications by authors named "N Gotohda"
Background: The combination of immune checkpoint inhibitors and chemotherapy has shown promising results for the treatment of advanced biliary tract cancer (BTC). Based on the results of the TOPAZ-1 trial, a gemcitabine and cisplatin plus durvalumab (GCD) regimen was recently approved as first-line therapy for patients with advanced BTC. However, post-GCD conversion surgery has not been previously studied.
View Article and Find Full Text PDFArticle Synopsis
- - The study focuses on developing a deep learning model to automatically identify bleeding areas during laparoscopic hepatectomy, which can help improve safety in surgeries by enhancing hemostasis.
- - Researchers used a dataset of 2203 annotated images from 44 laparoscopic videos, dividing them into training, validation, and test subsets, and employed a convolutional neural network for semantic segmentation.
- - The evaluation metrics showed the model achieved precision of 0.76, recall of 0.79, and Dice coefficient of 0.77, indicating its potential for real-time alerts and training assessments in surgical practice.
Is multidisciplinary treatment effective for invasive intraductal papillary mucinous carcinoma?
Ann Gastroenterol Surg
September 2024
Article Synopsis
- * Analyzing data from 1183 patients, it found that completing 6 months of postoperative adjuvant therapy significantly improved overall, disease-specific, and recurrence-free survival, especially for high-risk patients.
- * Additionally, neoadjuvant therapy showed benefits for those with borderline resectable IPMC, and any treatment for recurrence after surgery was linked to longer survival compared to no treatment.
Paragangliomas (PGLs) located around the pancreas are rare and challenging to diagnose preoperatively. Tumor resection with pancreatectomy is often performed for peripancreatic PGL. However, pancreas-sparing tumor resection can be indicated with an accurate preoperative diagnosis.
View Article and Find Full Text PDFBackground: Laparoscopic simultaneous resection (LSR) of primary colorectal tumors and synchronous colorectal liver metastases (sCRLM) has been recently performed. This study aimed to evaluate the postoperative outcomes after LSR and determine the risk factors for resection surface-related complications (RSRC), such as postoperative biliary fistula and liver-transection surface abscess.
Methods: Between 2009 and 2022, consecutive patients with sCRLM who underwent LSR were included.