Tumor vasculature plays a crucial role in tumor progression, affecting nutrition and oxygen transportation as well as the efficiency of drug delivery. While targeting pro-angiogenic growth factors has been a significant focus for treating tumor angiogenesis, recent studies indicate that metabolism also plays a role in regulating endothelial cell behavior. Like cancer cells, tumor endothelial cells undergo metabolic changes that regulate rearrangement for tip cell position during angiogenesis.
View Article and Find Full Text PDFHealth professionals, despite increasing challenges, with notable exceptions, always pursue peace through health because it is who we are-we are here to heal both at the individual and the community level. This applies to the long-standing Israeli-Palestinian conflict. Unfortunately, till now, nongovernmental organizations have had minimal impact on the conflict.
View Article and Find Full Text PDFBackground: The operating room (OR) is a major cost and revenue center for a hospital. One of the few modifiable costs in the OR is single-use, sterile surgical supplies (SUSSS). If SUSSS are opened on the scrub table and not used, then they are wasted.
View Article and Find Full Text PDFJ Ambul Care Manage
February 2023
Israeli settlements in the occupied Palestinian Territories (oPT) continue to expand and there is little communication between the 2 sides. Countries not directly engaged in the conflict are uninterested in a dignified solution to the Israeli-Palestinian conflict. This article argues that international organizations, donors, and third states should encourage the following peace-building approaches when considering health care initiatives in this conflict.
View Article and Find Full Text PDFImportance: Low back and neck pain are often self-limited, but health care spending remains high.
Objective: To evaluate the effects of 2 interventions that emphasize noninvasive care for spine pain.
Design, Setting, And Participants: Pragmatic, cluster, randomized clinical trial conducted at 33 centers in the US that enrolled 2971 participants with neck or back pain of 3 months' duration or less (enrollment, June 2017 to March 2020; final follow-up, March 2021).