Publications by authors named "N Golani"

Article Synopsis
  • This study examines how gender-affirming hormone treatment (GAHT) affects cortisol levels in transgender individuals, focusing on differences before and after treatment.
  • Ten transgender males and eight transgender females were tested for cortisol responses to adrenocorticotropic hormone (ACTH) before and after 6 months of GAHT.
  • Results showed that cortisol levels decreased in transgender males and increased in transgender females, indicating changes in their stress response and possibly reduced anxiety after treatment.
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Study Question: Is the functional ovarian reserve in transgender men affected by testosterone therapy?

Summary Answer: Serum anti-Müllerian Hormone (AMH) levels slightly decrease during testosterone treatment but remain within the normal range, suggesting preserved follicular ovarian reserve.

What Is Known Already: Few small studies have investigated the impact of gender-affirming treatment on reproduction in transgender men. Conflicting results were reached concerning ovarian morphology and AMH levels in this context.

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Background: Ghrelin is a potent GH secretagogue that also plays an important role in appetite and weight regulation. Ghrelin increases hunger and food intake, and its levels decrease after a standard meal or glucose.

Objective: To examine the effects of standard oral glucose, lipid and protein loads on ghrelin levels, investigating the possibility that these responses may be modulated by several anthropometric and metabolic factors.

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