When searching for a partner, people often rely on social cues to determine partners' suitability, finding those who attract attention from others particularly appealing. While people continue to evaluate their partners beyond relationship initiation, existing research has predominantly concentrated on the effects of observing others' choices during the stage of partner selection, neglecting to consider whether viewing others' attention toward current partners yields similar effects or instead elicits defensive devaluation. In three experiments, we exposed Israeli participants to situations where their partners received unsolicited flirtatious advances, utilizing visualization, virtual reality, and recall techniques.
View Article and Find Full Text PDFUtilizing trio whole-exome sequencing and a gene matching approach, we identified a cohort of 18 male individuals from 17 families with hemizygous variants in KCND1, including two de novo missense variants, three maternally inherited protein-truncating variants, and 12 maternally inherited missense variants. Affected subjects present with a neurodevelopmental disorder characterized by diverse neurological abnormalities, mostly delays in different developmental domains, but also distinct neuropsychiatric signs and epilepsy. Heterozygous carrier mothers are clinically unaffected.
View Article and Find Full Text PDFBackground: Biological similarities between inflammatory bowel disease (IBD) and familial Mediterranean fever (FMF) have been described in humans and animal models suggesting a possible common genetic basis. FMF is caused by variants in the MEFV gene which encodes pyrin, an immune regulator. This study aimed to investigate the carrier rate of disease-causing MEFV variants in children of different ethnicities diagnosed with very-early-onset IBD (VEO-IBD).
View Article and Find Full Text PDF: Numerous studies have aimed to predict prenatal and neonatal outcomes for pregnancies complicated by congenital cytomegalovirus (CMV). Presently, assessing CMV severity prenatally relies largely on fetal imaging. A controversy exists regarding CMV viral load (VL) and its association with fetal and neonatal sequelae.
View Article and Find Full Text PDFThe MAPK p38α was proposed to be a prominent promoter of skeletal muscle aging. The skeletal muscle tissue is composed of various muscle types, and it is not known if p38α is associated with aging in all of them. It is also not known if p38α is associated with aging of other tissues.
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