Publications by authors named "N Gaide"

High pathogenicity avian influenza viruses (HPAIVs) have caused major epizootics in recent years, with devastating consequences for poultry and wildlife worldwide. Domestic and wild ducks can be highly susceptible to HPAIVs, and infection leads to efficient viral replication and massive shedding (i.e.

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At the end of 2020, an outbreak of HPAI H5N8 was registered in captive African houbara bustards (Chlamydotis undulata) in the United Arab Emirates. In order to better understand the pathobiology of this viral infection in bustards, a comprehensive pathological characterization was performed. A total of six birds were selected for necropsy, histopathology, immunohistochemistry, RNAscope in situ hybridization and RT-qPCR and nanopore sequencing on formalin-fixed and paraffin-embedded (FFPE) tissue blocks.

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Article Synopsis
  • Immature feathers act as sites for high pathogenicity avian influenza virus (HPAIV) replication in poultry, but their exact role in viral transmission remains unclear.
  • The study focused on the feather epithelium's contribution to spreading clade 2.3.4.4b H5 HPAIVs in domestic ducks, revealing significant effects of infection, including tissue damage and viral shedding.
  • The findings suggest that feather epithelium is critical for viral replication and may serve as a source of infectious materials in the environment, thereby enhancing the spread of the virus among poultry flocks.
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Tumors in cows are not frequently reported in the literature. They often represent unusual findings in live animals and are incidental at slaughter with rare positive therapeutic outcomes for farmers. A 9-year-old beef cow was referred to the hospital of ruminants of the National Veterinary School of Toulouse, France.

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