Can Severe Uremia Impact Mortality Predictors in Elderly People With Kidney Failure?

Numerous studies have shown that dialysis may not be as beneficial to elderly, frail patients with chronic kidney failure and multiple comorbidities as comprehensive conservative therapy (CCT) and that dialysis may worsen the quality of life (QOL), increase hospitalization rates, and cause a significant decline in functional status. Several mortality predictors have been proposed to determine which patients would benefit more from CCT or dialysis. We estimated the short-term risk of death in an 81-year-old male patient with kidney failure and highly severe frailty using the REIN score, a dependable risk prediction model proposed by the European Renal Best Practice Group for the prediction of short-term risk mortality.

Single center experience in successful prevention of exit-site infection in patients on peritoneal dialysis.

The aim of our study was to use non-cytotoxic, easily available agent - 3% NaCl (hypertonic) saline compresses as prophylaxis measure for long-term prevention of ESI and avoid antibiotic resistance later. Advantages of hypertonic saline include excellent patient acceptance, ease of use, lack of adverse effects on exit site, adjacent skin, catheter or systemic reaction, and minimal expense. During the observational time of 36 months a total of 78 patients were enrolled in this study.

Association of anti-phospholipasea2-receptor antibodies with clinical course of idiopathic membranous nephropathy.

Aim of the study - assessment of the presence of M-type phospholipase A2 receptor antibodies in Georgian patients with biopsy proven IMN and their correlation with the disease activity for the appliance and monitoring of immunosuppressive therapy. A total 37 patients, after exclusion of the possible secondary factors, with biopsy proven IMN entered the study. All patients received standard immunosuppressive therapy: cyclosporine combined with methylprednisolone.

[Immobilization of champagne yeasts by inclusion into cryogels of polyvinyl alcohol for preventing cell escape from carrier matrix].

Wine champagnizing, a process involving the use of champagne yeasts immobilized by inclusion into cryogels of polyvinyl alcohol, has been studied. Treatment of yeast cells with the autoregulatory factor d1 was proposed as a means of preventing the cell escape from the carrier matrix. Such a treatment inhibited growth and proliferation processes in yeasts cells, without affecting the activity of fermentation; the resulting champagne had the same organoleptic and chemical characteristics as its counterparts obtained using traditional techniques.