Publications by authors named "N G Romanov"
Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative bacteria are lacking, despite their ribosomes being major antimicrobial drug targets.
View Article and Find Full Text PDFAutophagy is initiated by the assembly of multiple autophagy-related proteins that form the phagophore assembly site where autophagosomes are formed. Atg13 is essential early in this process, and a hub of extensive phosphorylation. How these multiple phosphorylations contribute to autophagy initiation, however, is not well understood.
View Article and Find Full Text PDFBackground: Identifying skeletal remains has been and will remain a challenge for forensic experts and forensic anthropologists, especially in disasters with multiple victims or skeletal remains in an advanced stage of decomposition. This study examined the performance of two machine learning (ML) algorithms in predicting the person's sex based only on the morphometry of L1-L5 lumbar vertebrae collected recently from Romanian individuals. The purpose of the present study was to assess whether by using the machine learning (ML) techniques one can obtain a reliable prediction of sex in forensic identification based only on the parameters obtained from the metric analysis of the lumbar spine.
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- Various cellular quality control mechanisms, like ribosome-associated chaperones, help maintain proteostasis by preventing misfolding of proteins during translation.
- This study hypothesizes that importins, which usually assist in transporting proteins into the nucleus, might also bind to newly formed protein chains during translation, rather than just after.
- By analyzing all importins in yeast, the researchers found some that associate with potentially unstable proteins, indicating that importins and other chaperones work together to ensure proper protein folding and prevent aggregation.
Semiconductor colloidal nanoplatelets based of CdSe have excellent optical properties. Their magneto-optical and spin-dependent properties can be greatly modified by implementing magnetic Mn ions, using concepts well established for diluted magnetic semiconductors. A variety of magnetic resonance techniques based on high-frequency (94 GHz) electron paramagnetic resonance in continuous wave and pulsed mode were used to get detailed information on the spin structure and spin dynamics of Mn ions in core/shell CdSe/(Cd,Mn)S nanoplatelets.
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