Publications by authors named "N G Mikeshina"

The basic concepts, notions and methods of geometric morphometrics (GM) are considered. This approach implies multivariate analysis of landmark coordinates located following certain rules on the surface of a morphological object. The aim of GM is to reveal differences between morphological objects by their shapes as such, the "size factor" being excluded.

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The effect of extracellular calcium binding and temperature of isolation and storage of thymus lymphocytes on their viability was studied. The last was evaluated by the fluorescence intensity of fluoresceindiacetate stained cells and by the intracellular ATP content. The rise of temperature of isolation and storage of lymphocytes from 1 degree to 22 degrees C significantly lowered the intracellular ATP concentration in cells storing in dense suspension [(3-4) x 10(9) lymphocytes/ml].

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The problem of efficacy prediction for psychopharmacotherapy of depressions is of considerable interest and urgency in view of frequently occurring resistance to antidepressants. The purpose of the present study was to study the feasibility of predicting the effectiveness of depression therapy in manic-depressive psychosis (MDP), based on the cross-sectional analysis of the patient's history (the clinical picture of the patient's condition prior to therapy) with the help of multivariate statistics. Eighty-two patients suffering from MDP with a variety of depressive states were examined.

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