Publications by authors named "N G Melikian"
Background: Recent observations in silico and in vivo reported that, during proximal optimisation technique, drug-eluting stents (DES) elongate, challenging conventional wisdom. The interaction between plaque morphology and radial expansion is well established, but little is known about the impact of plaque morphology on elongation.
Aims: We aimed to assess the longitudinal mechanical behaviour of contemporary DES in vivo and evaluate the relationship between post-percutaneous coronary intervention (PCI) stent elongation and lesion morphology, as assessed with optical coherence tomography (OCT).
Background: Heart failure with preserved ejection fraction (HFpEF) is the predominant form of HF in older adults. It represents a heterogenous clinical syndrome that is less well understood across different ethnicities.
Objectives: This study aimed to compare the clinical presentation and assess the diagnostic performance of existing HFpEF diagnostic tools between ethnic groups.
Background: Cardiac troponin is commonly raised in patients presenting with malignancy. The prognostic significance of raised troponin in these patients is unclear.
Objectives: We sought to investigate the relation between troponin and mortality in a large, well characterised cohort of patients with a routinely measured troponin and a primary diagnosis of malignancy.
Validation of the CREST model and comparison with SCAI shock classification for the prediction of circulatory death in resuscitated out-of-hospital cardiac arrest.
Eur Heart J Acute Cardiovasc Care
August 2024
Article Synopsis
- The study tested the CREST model, a scoring system with five variables, to see how well it predicts the risk of circulatory aetiology death (CED) in patients who suffered an out-of-hospital cardiac arrest (OHCA), compared to the SCAI shock classification.
- Researchers analyzed data from a registry of 723 patients with cardiac-related OHCA to determine how well each model predicted CED within 30 days; they found a strong link between higher CREST scores and increased risk of CED.
- Results indicated that both the CREST model and the SCAI classification performed similarly, providing effective prediction for CED following OHCA, with no significant differences in their accuracy