[The efficacy of tiotropium bromide (spiriva) in the treatment of patients with chronic obstructive pulmonary disease of varying severity: results of the Russian trial].

Aim: To evaluate the efficacy and safety of Spiriva (thiotropium bromide 18 microg for inhalation via a HandiHaler device) in patients with chronic obstructive pulmonary disease (COPD) of all severities in routine clinical practice in Russia.

Subjects And Methods: The study enrolled 407 patients (68 women and 339 men) with COPD who used thiotropium bromide (Spiriva) for 8 weeks. Most (72.

[Use of nebulizer in berodual treatment of patients with chronic obstructive bronchitis in exacerbation].

Aim: To study efficiency and safety of berodual in solution for inhalations delivered with the help of nebulizer in patients with exacerbation of chronic bronchitis (CB).

Materials And Methods: 12 patients with chronic bronchitis who had not responded to oral methylxantines in combination with expectorants received berodual for 10 days (1 ml 3 times a day).

Results: In the course of berodual treatment all the CB symptoms relieved and external respiration function improved.

[Experience in long-term use of berodual in the treatment of patients with chronic obstructive bronchitis].

Aim: To study clinical efficiency of 12-month administration of berodual in chronic obstructive bronchitis (COB).

Materials And Methods: The trial entered 33 patients with at least 2-year history of COB and forced expiratory volume per 1 sec (FEV1) not less than 45% of normal value.

Results: The best response of clinical parameters and external respiration was observed throughout 3 weeks of berodual inhalations.