Publications by authors named "N G Karp"
Implant-based breast reconstruction has been essential since the 1960s, offering a faster and less invasive alternative to autologous reconstruction. Recent innovations-including direct-to-implant (DTI) reconstruction, advancements in surgical planes, synthetic meshes, and nipple-areolar complex (NAC) neurotization-have improved patient outcomes. This review explores these developments, analyzing their impact on breast reconstruction over the past two decades.
View Article and Find Full Text PDFIn anticancer research, tumor growth measured in mouse models is important for assessing treatment efficacy for a treatment to progress to human clinical trials. Statistical analysis of time-to-event tumor volume data is complex because of heterogeneity in response and welfare-related data loss. Traditional statistical methods of testing the mean difference between groups are not robust because they assume common responses across a population.
View Article and Find Full Text PDFArticle Synopsis
- Pilot studies are preliminary experiments aimed at informing the design of larger, future studies to enhance effectiveness.
- The text outlines five common mistakes in conducting pilot studies, primarily related to poor planning and misinterpretation of results, which can hinder research goals.
- It emphasizes the importance of well-executed pilot studies to accurately estimate variability and avoid inconclusive outcomes in subsequent experiments.
Background: Breast implant illness (BII) has become a contentious subject in recent years. Although some studies have reported associations between breast implants and autoimmune diseases, others have failed to establish a definitive link.
Objectives: The objective of this study was to provide a comprehensive, up-to-date evaluation of the literature surrounding BII, with an emphasis on identifying patient-related factors that may be associated with BII.