[Neurotensin influence on painful stress afteractions in rats with neurotoxic damages of serotoninergic structures of brain substantia nigra].

The purpose of the research was to reveal the features of neurotensin influence on behavior of rats with damages of 5-HT structures of substantia nigra. Changes of recall of passive avoidance conditioned reactions, and also painful stimulation aftereffects on locomotor activity of rats in "open field" were studied. It was shown that neurotoxin 5,7-DOT administration into substantia nigra impaired recall of passive avoidance reactions and as well weakened oppressive aftereffects of painful stimulation.

[Reproduction of passive avoidance reactions after neurotensin microinjection into nucleus accumbens of rat brain against the background of reserpine action].

The purpose of the study was to reveal the features of the influence of neurotensin injected into the nucleus accumbens on behaviour of rats after systemic administration of reserpine in the dose of 2 mg/kg. Reprodution of passive avoidance conditioned reactions, painful stimulation aftereffects on locomotor activity in the "open field", and behavior in the elevated plus-maze were studied. It was shown that reserpine administration impaired the reproduction of passive avoidance reactions and weakened the oppressing aftereffect of painful stimulation, which can be due to a decrease in anxiety in rats.

[Effect of neurotensin on the behavior of rats with damaged serotoninergic neurons under immobilization stress].

It was shown that the immobilization of animals has led to reducing of vertical and horizontal locomotor activity in the "open field" and decreasing of number of conditioned food-procuring reactions into T-maze. The damages of serotoninergic neurons produced via local injections of selective neurotoxin 5, 7-dihydroxytriptamine into dorsal raphe nucleus intensified behavior alterations. Neurotensin administrations reduced effects of neurotoxin: the rats locomotor activity and quantity of conditioned reactions into T-maze were kept at the phone level just after immobilization as well as next two days.

[Systemic and andragogic issues related to professional training of medical personnel in the sphere of hygiene of children and adolescents].

The continuous education concept presupposes that a person is educated during his or her entire conscious lifetime. The pedagogical education model is made use of at the higher-school stage; while at the postgraduate stage, the andragogic model must be involved. The andragogics is a branch of science, according to which the leading role belongs to the person who is educated.