Gait Kinematic Dependent Plantar Stimulation.

Vibro-tactile stimulation is often used to stimulate the plantar surfaces during walking to augment or replace the pattern of natural sensory feedback. However, many of these methods supply patterns of vibro-tactile feedback that are independent of the individual's real-time gait kinematics. If the purpose of the stimulation is to augment the natural feedback provided by the tactile receptors, the additional vibrations should change depending on the real-time movements similar to those natural receptors.

Free-ranging squirrels perform stable, above-branch landings by balancing using leg force and nonprehensile foot torque.

For gap-crossing agility, arboreal animals require the ability to stabilize dynamic landings on branches. Despite lacking a prehensile grip, squirrels achieve stable landings using a palmar grasp. We investigated the landing dynamics of free-ranging fox squirrels (Sciurus niger) to uncover strategies for stable, above-branch landings.

Effect of Vibro-Tactile Stimulation Sequence and Support Surface Inclination on Gait and Balance Measures.

The plantar surfaces of the feet are important for balance control during walking, specifically by allowing for the perception of pressure movements during stance. : The current study aimed to perturb CoP movement perception in healthy individuals by applying vibrations to the soles of the feet in different stimulation sequences: a natural pattern that followed CoP movement () and a perturbing pattern that did not follow the CoP () during walking. We hypothesized that the stimulation sequence would be similar to walking without any stimulation and therefore have no effect on balance measures and that the sequence would negatively affect balance measures such as the anteroposterior (AP) and mediolateral (ML) margins of stability (MoSs) and foot placement area.

Accuracy of Automated External Defibrillator Pad Placement During Out-of-Hospital Cardiac Arrest Resuscitation Simulations.

Objectives: Out-of-hospital cardiac arrest (OHCA) victims receiving defibrillation from an automated external defibrillator (AED) placed early in the chain of survival are more likely to survive. We sought to explore the accuracy of AED pad placement for lay rescuers (LR) and first responders (FR).

Methods: We conducted a secondary analysis of data collected during randomized OHCA simulation trials involving LRs and FRs.

COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients.

Background: Colorectal cancer (CRC) is the third most common cancer in the United Kingdom and the second largest cause of cancer death.

Aim: To develop and validate a model using available information at the time of faecal immunochemical testing (FIT) in primary care to improve selection of symptomatic patients for CRC investigations.

Methods: We included all adults (≥ 18 years) referred to Nottingham University Hospitals NHS Trust between 2018 and 2022 with symptoms of suspected CRC who had a FIT.