Publications by authors named "N G Cheoklong"
J Immunother Cancer
June 2024
Article Synopsis
- - The study investigates the safety and effectiveness of combining toripalimab, an immune checkpoint inhibitor, with axitinib for treating non-metastatic clear cell renal cell carcinoma, focusing on clinical outcomes and biomarkers.
- - Conducted as a single-arm phase II trial with 20 enrolled patients, results showed a 45% objective response rate (ORR), with significant tumor shrinkage in 95% of participants before surgery.
- - Adverse events occurred in 25% of patients, including hypertension and elevated liver enzymes, while responders exhibited notable differences in certain immune factors compared to those with stable disease.
