Publications by authors named "N Fuwa"
Article Synopsis
- Streptococcal toxic shock syndrome (STSS) is a severe condition mainly caused by beta-hemolytic streptococci (BHS), with the study investigating other BHS species' roles in STSS development.
- The study analyzed medical records from 2002 to 2022, identifying 43 STSS cases and examining their clinical features compared to 285 non-STSS cases, while factoring in age and diabetes.
- Results showed a high mortality rate of about 35% in STSS cases, with certain BHS species being more strongly associated with STSS than others, highlighting the need for further understanding of these infections.
Article Synopsis
- Immune checkpoint inhibitors can effectively treat recurrent and metastatic head and neck cancers, but they come with risks of immune-related adverse events (irAEs) due to systemic administration.
- A study was conducted where tumor-bearing mice received either a standard dose or a low local dose of PD-L1 antibodies to evaluate their antitumor efficacy and immune response.
- Results showed that the local low-dose treatment was just as effective as the systemic standard-dose treatment in reducing tumors, with increased levels of important immune proteins in the low-dose group, indicating a promising strategy for treating oral squamous cell carcinoma.
Article Synopsis
- EG.5.1 is a new subvariant of the Omicron XBB variant of SARS-CoV-2 that is becoming more common globally, but its pathogenicity and immune evasion are still not well understood.
- Research shows that EG.5.1 has similar growth ability and pathogenicity as XBB.1.5 in hamsters, but it spreads more effectively than the older BA.2 variant.
- Additionally, plasma from recovered patients shows less neutralizing activity against EG.5.1 compared to XBB.1.5, suggesting that these differences might be contributing to its rise in prevalence among humans.
Superselective intra-arterial chemoradiotherapy (SSIACRT) is one of the curative treatments for advanced oral cancer. SSIACRT can reportedly treat cervical lymph node metastases in the level I-IIA area by super selectively catheterizing the facial artery (FA) and infusing drugs. However, since advanced oral cancer lesions involve a number of feeding vessels, retrograde treatment requires the placement of catheters from the superficial temporal artery (STA) and occipital artery (OA).
View Article and Find Full Text PDFWe report 4 cases of hypopharyngeal cancer preoperatively suspected with synchronous lymph node metastases. Pathologic lymph node metastasis was confirmed in three of the four cases. All 4 cases underwent endoscopic laryngopharyngeal surgery (ELPS) combined with endoscopic submucosal dissection (ESD) and subsequent lymph node dissection as an optional treatment rather than the standard treatment.
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