Publications by authors named "N Fukutake"
Article Synopsis
- Recent studies show a link between long-term Crohn's disease and an increased risk of cancer due to chronic inflammation and dysplasia.
- A case is reported involving a man in his 50s who developed multiple metastases of rectal cancer 5 years after surgery while managing Crohn's disease with various medications, including infliximab.
- This case highlights the higher risk and poorer prognosis for colorectal cancer patients with Crohn's disease, emphasizing the need for specialized diagnostic and treatment strategies that consider both conditions in future care.
A new formulation of the lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample model called the dispersed scatterer model (DSM), in which the sample is represented as a material with a spatially slowly varying refractive index and randomly distributed scatterers embedded in the material. It is shown that the formulation represents a meaningful OCT image and speckle as two independent mathematical quantities.
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- Family history of pancreatic cancer (PC) is recognized as a significant risk factor, prompting the need for an effective screening system to detect PC and related pancreatic abnormalities in the Japanese population.
- In a study involving 43 individuals, forward-viewing radial endoscopic ultrasound (FR-EUS) and MRI were used to screen for pancreatic issues, revealing a range of conditions including resectable PC, pancreatic cysts, and early signs of chronic pancreatitis (CP).
- Results indicated that FR-EUS was particularly effective in detecting early CP-like appearances and that the occurrence of pancreatic cysts and intraductal papillary mucinous neoplasm (IPMN) correlated with age and gender, underscoring the importance of targeted screening
Article Synopsis
- * Despite anticoagulation therapy causing increased tumor bleeding, the anemia did not improve, prompting frequent red blood cell transfusions and investigation that ruled out hemobilia as a source of bleeding.
- * The treatment involved placing a fully covered self-expandable metallic stent (SEMS) to achieve hemostasis, demonstrating that this approach can effectively manage bleeding from an ulcerated cancer surface, possibly by compressing the tumor and reducing blood vessel size.
Article Synopsis
- This study focuses on the risk of venous thromboembolism (VTE) in patients with unresectable metastatic pancreatic cancer undergoing chemotherapy with gemcitabine and nab-paclitaxel (GnP).
- It analyzed data from 174 patients to examine the impact of early VTE detection on overall survival (OS) and progression-free survival (PFS), finding that patients with early VTE had significantly worse outcomes.
- The results suggest that screening for VTE, even in asymptomatic patients, is essential as it may indicate a poorer prognosis in those receiving first-line chemotherapy.