Publications by authors named "N Freitag"

Article Synopsis
  • External muscle stimulation, along with active muscle contractions, may enhance physical functioning and performance in individuals with inclusion body myositis (IBM), a progressive muscle disease.
  • A case study of a 78-year-old male IBM patient revealed some improvement in peak oxygen uptake and functional test results after a two-year exercise training program that utilized this approach.
  • Though the exercise intervention showed potential benefits, the overall decline in health due to recurrent prostate cancer complicated the outcomes, highlighting the need for specialized supportive exercise programs for IBM patients.
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Carbon catabolite repression (CCR) is a widely conserved regulatory process that ensures enzymes and transporters of less-preferred carbohydrates are transcriptionally repressed in the presence of a preferred carbohydrate. This phenomenon can be regulated via a CcpA-dependent or CcpA-independent mechanism. The CcpA-independent mechanism typically requires a transcriptional regulator harboring a phosphotransferase regulatory domain (PRD) that interacts with phosphoransferase ystem (PTS) components.

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Adverse intrauterine conditions may cause fetal growth restriction (FGR), a pregnancy complication frequently linked to perinatal morbidity and mortality. Although many studies have focused on FGR, the pathophysiological processes underlying this disorder are complex and incompletely understood. We have recently determined that galectin-3 (gal-3), a β-galactoside-binding protein, regulates pregnancy-associated processes, including uterine receptibility, maternal vascular adaptation and placentation.

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Despite extensive sorting, packaging waste often contains a mixture of different materials that make high-quality recycling difficult, especially in the case of flexible packaging. This is partly due to the widespread use of multi-layer laminates and packaging consisting of different inseparably combined materials. To improve the post-consumer recyclate quality and develop optimised recycling processes, it is important to generate a comprehensive understanding of the composition of the sorted packaging waste streams.

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Article Synopsis
  • Abnormal placental blood vessel development caused by high levels of anti-angiogenic factors like sFLT1 is associated with preeclampsia, a serious condition that affects pregnant women and their babies after 20 weeks.
  • Previous studies on mice showed that increased hsFLT1 leads to reduced placental function and symptoms similar to preeclampsia.
  • This research found elevated levels of the protein galectin-1 in specific areas of the placenta in hsFLT1 mice, suggesting that the galectin-glycan network may help counteract the harmful effects of anti-angiogenic factors during pregnancy.
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